Model AD Explorer Resources
About the Model AD Explorer
The Model AD Explorer is a web application that hosts high-dimensional human transcriptomic, proteomic, and metabolomic evidence for whether or not genes are associated with Alzheimer’s disease (AD). Agora also contains a list of over 900 nascent drug targets for AD that were nominated by AD researchers. The list of nominated targets was contributed by researchers from the National Institute on Aging's Accelerating Medicines Partnership in Alzheimer's Disease (AMP-AD) consortium and Target Enablement to Accelerate Therapy Development for Alzheimer's Disease (TREAT-AD) centers, as well as other research teams. Other evidence presented in Agora was either generated by AMP-AD and TREAT-AD research teams, or is aggregated from publicly available data sources.
Agora is funded by the National Institute on Aging. It is developed and maintained by Sage Bionetworks. If you have questions, suggestions, or feedback about Agora, please let us know here.
Acknowledging MODEL-AD
We encourage you to use the data and insights presented in the ModelAD Explorer, and request that you include the following acknowledgement statement when publicly presenting work that benefited from their use:
The results published here are in whole or in part based on data obtained from Agora, a platform initially developed by the NIA-funded AMP-AD consortium that shares evidence in support of AD target discovery. Agora is available at: doi:10.57718/agora-adknowledgeportal
Data and Methods
The following pages contain additional information about the evidence presented the Model-AD explorer: